Synthesis & Analytical Chemistry
R-nuucell has accessible a set of instrumentation and
equipment to support the synthesis, purification and
full characterization of our new metallodrugs.
Drug Screening
All drugs are tested in vitro against a wide panel of
several human cancer cell lines with different genetic
alterations and degrees of aggressiveness and in
healthy human cell lines.
Lead Compound Optimization
The most promising structures are selected based on
their cytotoxicity, selectivity, mode of action,
identified targets, among others. Formulation studies
to allow for in vivo administration are performed.
IP Protection
Our new drugs technology is patented (active drug +
targeted disease).
In Vivo Proof-of-Concept
The hit compounds are tested in in vivo models for
toxicity and activity in our laboratories.
Pre-Clinical Studies Validation
The selected compounds are tested in accredited
laboratories thorough detailed in vitro, ex vivo and
in vivo efficacy, toxicity and pharmacokinetics
assays.